Black Cohosh and Climacteric Symptoms: Growing Knowledge about the Efficacy and Safety

Efficacy and Safety of Isopropanolic Black Cohosh Extract for Climacteric Symptoms

METHODS: This randomized, multicenter, double-blind clinical trial compared the efficacy and tolerability of the isopropanolic black cohosh extract in the treatment of climacteric complaints compared with placebo. A total of 304 patients were randomly allocated to receive tablets corresponding to 40mg drug ormatching placebo daily for 12 weeks. The primary efficacy measure was the change from b...

Efficacy and safety of isopropanolic black cohosh extract for climacteric symptoms.

OBJECTIVE Several clinical studies suggest that black cohosh may be effective in climacteric complaints. However, evidence of its efficacy based on current quality standards has been limited. METHODS This randomized, multicenter, double-blind clinical trial compared the efficacy and tolerability of the isopropanolic black cohosh extract in the treatment of climacteric complaints compared with...

Black cohosh and St John's wort reduced climacteric and depressive symptoms.

Black Cohosh and St. John's Wort (GYNO-Plus®) for Climacteric Symptoms

PURPOSE This study was conducted to investigate the efficacy of black cohosh (Cimicifuga racemosa) and St. John's wort (Hypericum perforatum) in women with climacteric symptoms, and to assess their effects on vaginal atrophy, hormone levels, and lipid profiles. MATERIALS AND METHODS In this double-blind randomized, placebo-controlled, multicenter study, 89 peri- or postmenopausal women experi...

Black Cohosh Considerations of Safety and Benefit

Joseph M. Betz, PhD Linda Anderson, PhD Mark I. Avigan, MD Joanne Barnes, PhD Norman R. Farnsworth, PhD Barbro Gerdén, MD Leigh Henderson, MS Edward J. Kennelly, PhD Uwe Koetter, PhD Stephanie Lessard, MS Tieraona Low Dog, MD, PhD Michelle McLaughlin, BS Belal Naser, MD Ruediger G. W. Osmers, MD, PhD Linda S. Pellicore, PhD John R. Senior, PhD Richard B. van Breemen, PhD Wolfgang Wuttke, MD Joh...